What is the total number of U.S. Senators?

The total number of U.S. Senators is one hundred (100). This is established by the U.S. Constitution, specifically in Article I, Section 3, where it states that the Senate of the United States shall be composed of two Senators from each state, regardless of the state's population. Since the United States has fifty states, this results in a Senate comprised of two Senators per state, culminating in a total of one hundred Senators. This structure ensures equal representation for each state in the legislative process, distinguishing the Senate from the House of Representatives, which is based on population.